Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706332 | 0.83 | SIGMAR1 (0.48) | HTR7SIGMAR1HTR1ASLC18A3DRD2 | |
| Hydrochloric Acid SCHEMBL8706250 | 0.83 | HTR7 (0.52) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8708208 | 0.82 | HTR7 (0.46) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| SCHEMBL8702980 | 0.82 | SIGMAR1 (0.44) | HTR7SIGMAR1BRD4 | |
| Hydrochloric Acid SCHEMBL8702487 | 0.81 | HTR7 (0.50) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8707795 | 0.80 | HTR7 (0.49) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| SCHEMBL8702050 | 0.80 | HTR7 (0.53) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8701973 | 0.79 | HTR7 (0.43) | HTR7SIGMAR1DRD2BRD4 | |
| SCHEMBL8701730 | 0.78 | HTR7 (0.47) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8702450 | 0.78 | HTR7 (0.47) | HTR7SIGMAR1HTR1AHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |