Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8707795 | 0.86 | HTR7 (0.49) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8702450 | 0.85 | HTR7 (0.47) | HTR7SIGMAR1ALDH1A1HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8706250 | 0.85 | HTR7 (0.52) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8702487 | 0.83 | HTR7 (0.50) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8710792 | 0.82 | HTR7 (0.48) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8701630 | 0.82 | HTR7 (0.48) | HTR7SIGMAR1PARP1PARP2 | |
| SCHEMBL8701565 | 0.78 | HTR7 (0.55) | HTR7SIGMAR1HTR1AHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL8706822 | 0.74 | SIGMAR1 (0.49) | HTR7SIGMAR1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL5729537 | 0.73 | HTR7 (0.63) | HTR7SIGMAR1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7989673 | 0.73 | HTR1A (0.62) | HTR7SIGMAR1SMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |