Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 4/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8706668 | 0.84 | HTR7 (0.57) | DRD2HTR7 | |
| Hydrochloric Acid SCHEMBL8701973 | 0.83 | HTR7 (0.43) | DRD2HTR7 | |
| SCHEMBL8702980 | 0.78 | SIGMAR1 (0.44) | HTR7 | |
| Hydrochloric Acid SCHEMBL8708208 | 0.78 | HTR7 (0.46) | DRD2HTR7 | |
| SCHEMBL8701565 | 0.76 | HTR7 (0.55) | DRD2HTR7 | |
| Hydrochloric Acid SCHEMBL8707983 | 0.76 | HTR7 (0.51) | DRD2HTR7 | |
| Hydrochloric Acid SCHEMBL8706250 | 0.73 | HTR7 (0.52) | DRD2HTR7 | |
| Hydrochloric Acid SCHEMBL8708209 | 0.72 | HTR7 (0.56) | DRD2HTR7DRD4 | |
| Hydrochloric Acid SCHEMBL8702092 | 0.71 | HTR7 (0.47) | DRD2HTR7 | |
| Hydrochloric Acid SCHEMBL8702749 | 0.71 | HTR7 (0.54) | DRD2HTR7DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |