Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696372 | 0.80 | NPC1 (0.52) | MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL8542109 | 0.80 | HRH3 (0.51) | MEN1KMT2ATSHR | |
| SCHEMBL8701656 | 0.77 | SIGMAR1 (0.39) | TSHR | |
| SCHEMBL8701671 | 0.77 | ADRA2A (0.42) | MEN1KMT2A | |
| SCHEMBL9820990 | 0.75 | SIGMAR1 (0.47) | — | |
| SCHEMBL8698787 | 0.74 | MEN1 (0.42) | MEN1KMT2AALDH1A1NPSR1HSD17B10 | |
| SCHEMBL8699170 | 0.74 | SIGMAR1 (0.40) | MEN1KMT2AALDH1A1NPSR1HSD17B10 | |
| SCHEMBL8695270 | 0.74 | ADRA2A (0.45) | MEN1KMT2AALDH1A1NPSR1HSD17B10 | |
| SCHEMBL4339380 | 0.74 | SIGMAR1 (0.54) | — | |
| SCHEMBL5888846 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |