Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695755 | 0.83 | ALOX5 (0.63) | ALOX5KMT2AMLYCDALDH1A1HDAC2 | |
| SCHEMBL8696844 | 0.80 | PPIB (0.38) | ALOX5ACHEMLYCDALDH1A1CYP4F2 | |
| SCHEMBL8696461 | 0.79 | ALOX5 (0.56) | ALOX5KMT2AMLYCDALDH1A1HDAC2 | |
| SCHEMBL8695773 | 0.79 | ESR2 (0.40) | BCHEACHEKMT2AALDH1A1KDM4E | |
| SCHEMBL8696916 | 0.76 | PPIB (0.39) | MLYCDALDH1A1POLQHDAC2KDM4E | |
| Trifluoroacetic Acid SCHEMBL8695772 | 0.76 | FFAR1 (0.40) | KMT2AMLYCDALDH1A1POLQKDM4E | |
| SCHEMBL8699095 | 0.76 | MLYCD (0.64) | ALOX5MEN1KMT2AMLYCDALDH1A1 | |
| SCHEMBL22445695 | 0.75 | MLYCD (0.46) | KMT2AMLYCDALDH1A1KDM4EHPGD | |
| SCHEMBL4253986 | 0.75 | MAPT (0.56) | ALDH1A1CYP4F2CYP4A11HDAC2HDAC1 | |
| SCHEMBL8701223 | 0.75 | HDAC1 (0.62) | ALDH1A1HDAC2HTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |