Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704811 | 0.90 | TACR3 (0.52) | TACR3NPC1RAB9AMGLLPTPN1 | |
| SCHEMBL1705538 | 0.82 | TACR3 (0.54) | TACR3NPC1RAB9AMGLLPTPN1 | |
| SCHEMBL27468452 | 0.79 | TACR3 (0.51) | TACR3NPC1RAB9AMGLLPTPN1 | |
| SCHEMBL3639800 | 0.78 | TACR3 (0.50) | TACR3NPC1RAB9AMGLLPTPN1 | |
| SCHEMBL7310630 | 0.75 | NPC1 (0.61) | NPC1RAB9AMGLLPTPN1POLB | |
| SCHEMBL27857608 | 0.73 | P2RX7 (0.48) | TACR3NPC1RAB9AMGLLPOLB | |
| SCHEMBL27789206 | 0.73 | ROCK2 (0.62) | NPC1RAB9AMGLLPTPN1POLB | |
| SCHEMBL3766520 | 0.72 | TACR3 (0.47) | TACR3NPC1RAB9AMGLLPTPN1 | |
| SCHEMBL7296951 | 0.70 | MAPT (0.80) | NPC1RAB9AMGLLPOLBROCK2 | |
| SCHEMBL3105408 | 0.69 | RAB9A (0.60) | TACR3NPC1RAB9AMGLLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045266-A1 | 3-AMINOPYRIDINE DERIVATIVES FOR TREATMENT OF INFLAMMATORY AND MALIGNANT DISEASES | FERRING B.V. (NL) | 1998-10-15 | — | — | WO | disclosed |