Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696779 | 0.85 | SLC6A2 (0.44) | CYP19A1ALDH1A1PKMMAPTKMT2A | |
| SCHEMBL8703089 | 0.84 | CYP19A1 (0.43) | CYP19A1ALDH1A1PKMMAPTHPGD | |
| SCHEMBL8700549 | 0.84 | CYP19A1 (0.66) | CYP19A1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL8700864 | 0.80 | CYP19A1 (0.69) | CYP19A1TSHRHTTLMNA | |
| SCHEMBL8697118 | 0.72 | CYP19A1 (0.55) | CYP19A1TSHRMEN1KMT2A | |
| SCHEMBL8627683 | 0.68 | CYP2C19 (0.48) | ALDH1A1PKMMAPTMEN1KMT2A | |
| SCHEMBL11050157 | 0.67 | ESR2 (0.41) | ALDH1A1PKMMAPTMEN1KMT2A | |
| SCHEMBL8697937 | 0.67 | CYP19A1 (0.60) | CYP19A1TSHR | |
| SCHEMBL30373952 | 0.66 | CYP19A1 (0.46) | CYP19A1KMT2APOLB | |
| SCHEMBL4982361 | 0.65 | KMT2A (0.48) | ALDH1A1PKMMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |