Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.69 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355389 | 0.82 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP3A4CYP2C19CYP11B1 | |
| SCHEMBL8696779 | 0.81 | SLC6A2 (0.44) | CYP19A1CYP11B2CYP2C19CYP11B1 | |
| SCHEMBL8701933 | 0.80 | CYP19A1 (0.43) | CYP19A1TSHRLMNAHTT | |
| SCHEMBL8700549 | 0.80 | CYP19A1 (0.66) | CYP19A1CYP3A4CYP2C19TSHRCYP1A2 | |
| SCHEMBL8703089 | 0.80 | CYP19A1 (0.43) | CYP19A1CYP11B2CYP2C19CYP11B1LMNA | |
| SCHEMBL2354748 | 0.75 | CYP19A1 (0.83) | CYP19A1CYP11B2CYP3A4CYP2C19CYP11B1 | |
| SCHEMBL8697788 | 0.74 | CYP19A1 (0.60) | CYP19A1CYP2C19CYP1A2 | |
| SCHEMBL8746248 | 0.71 | CYP19A1 (0.56) | CYP19A1CYP11B2CYP3A4CYP2C19CYP11B1 | |
| SCHEMBL8700875 | 0.70 | CYP19A1 (0.72) | CYP19A1CYP11B2CYP3A4CYP2C19CYP11B1 | |
| SCHEMBL9790964 | 0.68 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |