Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696779 | 0.85 | SLC6A2 (0.44) | CYP19A1ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL8703089 | 0.84 | CYP19A1 (0.43) | CYP19A1HTR1AHTR7HTR6TDP1 | |
| SCHEMBL8701933 | 0.84 | CYP19A1 (0.43) | CYP19A1HTR1AHTR7HTR6TSHR | |
| SCHEMBL3274982 | 0.80 | CYP19A1 (1.00) | CYP19A1TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL8700864 | 0.80 | CYP19A1 (0.69) | CYP19A1TSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8176557 | 0.78 | CYP19A1 (0.85) | CYP19A1 | |
| SCHEMBL8702471 | 0.72 | CYP19A1 (0.57) | CYP19A1TSHRKDM4ENPC1TP53 | |
| SCHEMBL8627683 | 0.68 | CYP2C19 (0.48) | MAPK1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL24516966 | 0.68 | KMT2A (0.42) | HTR1AHTR7HTR6TSHRMAPK1 | |
| SCHEMBL11050157 | 0.67 | ESR2 (0.41) | TDP1KDM4EALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |