Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683223 | 0.95 | ALDH1A1 (0.39) | ALDH1A1NAAAATMTSHRHPGD | |
| SCHEMBL8683098 | 0.94 | NAAA (0.41) | ALDH1A1NAAATSHREPHX2HCAR2 | |
| SCHEMBL8681178 | 0.94 | NAAA (0.41) | ALDH1A1NAAATSHREPHX2HCAR2 | |
| SCHEMBL8682098 | 0.94 | NAAA (0.41) | ALDH1A1NAAATSHREPHX2HCAR2 | |
| SCHEMBL8682200 | 0.94 | NAAA (0.41) | ALDH1A1NAAATSHREPHX2HCAR2 | |
| SCHEMBL8682191 | 0.94 | NAAA (0.41) | ALDH1A1NAAATSHREPHX2HCAR2 | |
| SCHEMBL8681136 | 0.91 | NAAA (0.39) | ALDH1A1NAAATSHREPHX2HCAR2 | |
| SCHEMBL8682240 | 0.91 | PPM1B (0.33) | NAAA | |
| SCHEMBL8686113 | 0.90 | NAAA (0.41) | ALDH1A1NAAATSHRHCAR2LMNA | |
| SCHEMBL8680776 | 0.90 | NAAA (0.41) | ALDH1A1NAAATSHRHCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |