⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427217 | 0.91 | MEN1 (0.56) | — | |
| SCHEMBL10590448 | 0.91 | MEN1 (0.56) | — | |
| SCHEMBL28044481 | 0.84 | — | — | |
| Pyridine SCHEMBL11350100 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL3969760 | 0.80 | HSD17B10 (0.72) | — | |
| SCHEMBL22234568 | 0.79 | CA12 (0.50) | — | |
| SCHEMBL8143643 | 0.79 | L3MBTL3 (0.55) | — | |
| SCHEMBL26287179 | 0.78 | — | — | |
| SCHEMBL9737159 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL786679 | 0.77 | SMN1; SMN2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4888 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719632-A1 | METHODS AND COMPOSITIONS FOR PURIFYING PARTICLES AND MACROMOLECULES | National Resilience, LLC (US) | 2026-04-08 | — | — | EP | claimed |
| WO-2025008499-A1 | METHODS AND COMPOSITIONS FOR PURIFYING PARTICLES AND MACROMOLECULES | ANJARIUM BIOSCIENCES AG (CH) | 2025-01-09 | — | — | WO | claimed |
| EP-3015467-B1 | MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD | AJINOMOTO KK (JP) | 2024-12-04 | — | — | EP | claimed |
| CN-104341374-A | Preparation method for morpholine carbonyl chloride compound | LIANHE CHEMICAL TECHNOLOGY DEZHOU CO LTD | 2015-02-11 | — | — | CN | claimed |
| WO-2012104865-A1 | N, N- DIALKYL -MORPHOLIN- 4 - CARBOXAMIDE COMPOUNDS AS INSECT REPELLING AGENTS AND A PROCESS FOR THEIR PREPARATION | DIRECTOR GENERAL, DEFENCE RESEARCH & DEVELOPMENT ORGANISATION (DRDO) (IN) | 2012-08-09 | — | — | WO | claimed |
| US-20120046284-A1 | Salts and hydrates of 4-[(3-chloro-4-fluoro-phenyl)amino]-6-(cis-4--cyclohexan-1-yloxy)-7-methoxy-quinazoline, their use as a medicament and the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-23 | — | — | US | claimed |
| EP-1896445-B1 | ( 6-FLU0R0-BENZ0[l, 3] DIOXOLYL) -MORPHOLIN-4-YL-METHANONES AND THEIR USE AS CBl LIGANDS | HOFFMANN LA ROCHE (CH) | 2010-11-10 | — | — | EP | claimed |
| WO-2010115869-A1 | PROPOFOL PHOSPHONYL DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS | SEPS PHARMA N.V. (BE) | 2010-10-14 | — | — | WO | claimed |
| US-20100056513-A1 | STEREOSPECIFICALLY SUBSTITUTED BENZO[1,3]DIOXOLYL DERIVATIVES | FREI BEAT | 2010-03-04 | — | — | US | claimed |
| EP-1896445-A1 | ( 6-FLU0R0-BENZ0[l, 3] DIOXOLYL) -MORPHOLIN-4-YL-METHANONES AND THEIR USE AS CBl LIGANDS | F. Hoffmann-Roche AG (CH) | 2008-03-12 | — | — | EP | claimed |
| WO-2006136502-A1 | ( 6-FLU0R0-BENZ0[l, 3] DIOXOLYL) -MORPHOLIN-4-YL-METHANONES AND THEIR USE AS CBl LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-28 | — | — | WO | claimed |
| US-20060293318-A1 | Stereospecifically substituted benzo[1,3]dioxolyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-28 | — | — | US | claimed |
| JP-55072178-A | — | — | None | — | — | JP | disclosed |
| US-20260146042-A1 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2026-05-28 | — | — | US | disclosed |
| EP-4747247-A1 | NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2026-05-27 | — | — | EP | disclosed |
| US-12637471-B2 | Heterocyclic compounds, compositions, methods of preparation and uses thereof | ORGANON R&D FINLAND LTD. (FI) | 2026-05-26 | — | — | US | disclosed |
| US-4024128-A | HYPOGLYCEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-05-17 | — | — | US | disclosed |
| US-4002641-A | DIURETICS, SALURETICS, HYPOTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3979202-A | Meta-bifunctional benzenes and herbicidal compositions | MONSANTO COMPANY (US) | 1976-09-07 | — | — | US | disclosed |