SCHEMBL8702455

SCHEMBL8702455

Cc1cc(O)nc2cc[c]cc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
BACE1 P56817 1/20 0.33
KDM4E B2RXH2 5/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 3/20 0.32
RAB9A P51151 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPFFR1 Q9GZQ6 1/20 0.32
NPFFR2 Q9Y5X5 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 2/20 0.31
NPC1 O15118 1/20 0.31
MITF O75030 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
AGTR1 P30556 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5547978 0.86 CYP1A2 (0.35) CYP1A2BACE1KDM4EALDH1A1HPGD
SCHEMBL10623525 0.81 MYC (0.31)
SCHEMBL6986503 0.79 ESR1 (0.36) MAPTLMNA
SCHEMBL8703308 0.78 ESR1 (0.40) RAB9AKMT2AMEN1NPC1
SCHEMBL5239938 0.76 ERAP1 (0.36) CYP1A2BACE1KDM4EALDH1A1HPGD
SCHEMBL8703720 0.76 AKR1C3 (0.39) KDM4EALDH1A1HPGDHSD17B10RAB9A
SCHEMBL8703065 0.74 ALDH1A1 (0.47) KDM4EALDH1A1HPGDMAPTTDP1
SCHEMBL8703180 0.73 NCOA1 (0.41) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL29692903 0.73 CYP1A2 (0.64) CYP1A2BACE1KDM4EALDH1A1HPGD
SCHEMBL377555 0.73 CYP1A2 (0.64) CYP1A2BACE1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed