SCHEMBL377555

SCHEMBL377555

Cc1cc(O)nc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
BACE1 P56817 1/20 0.60
ALDH1A1 P00352 2/20 0.54
NPFFR1 Q9GZQ6 1/20 0.54
NPFFR2 Q9Y5X5 1/20 0.54
KDM4E B2RXH2 5/20 0.51
MAPT P10636 3/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
RAB9A P51151 2/20 0.51
POLB P06746 1/20 0.51
TP53 P04637 1/20 0.51
GAA P10253 2/20 0.50
PRNP P04156 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HPGD P15428 1/20 0.49
ACHE P22303 1/20 0.49
LMNA P02545 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29692903 1.00 CYP1A2 (0.64) CYP1A2BACE1ALDH1A1NPFFR1NPFFR2
SCHEMBL4297830 0.98 CYP1A2 (0.62) CYP1A2BACE1ALDH1A1NPFFR1NPFFR2
SCHEMBL9376131 0.81 NQO2 (0.45) CYP1A2BACE1ALDH1A1KDM4EMAPT
SCHEMBL10763478 0.80 PSMB5 (0.49) CYP1A2BACE1ALDH1A1KDM4EL3MBTL1
SCHEMBL64767 0.78 MYC (0.52) CYP1A2ALDH1A1KDM4EMAPTL3MBTL1
SCHEMBL29502790 0.78 CYP1A2 (1.00) CYP1A2BACE1ALDH1A1NPFFR1NPFFR2
SCHEMBL1088580 0.78 CYP1A2 (0.69) CYP1A2BACE1ALDH1A1NPFFR1NPFFR2
SCHEMBL29376440 0.78 MYC (0.52) CYP1A2ALDH1A1KDM4EMAPTL3MBTL1
SCHEMBL89010 0.78 CYP1A2 (1.00) CYP1A2BACE1ALDH1A1NPFFR1NPFFR2
SCHEMBL13802956 0.78 KDM4E (0.54) CYP1A2ALDH1A1KDM4EMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409582-B Method for preparing peroxyacetic acid by heterogeneous catalyst and improving stability of peroxyacetic acid 兰州助剂厂股份有限公司 2024-05-14 CN claimed
CN-113686943-B Multifunctional nucleic acid dye and preparation method and application thereof 苏州优逸兰迪生物科技有限公司 2024-01-26 CN claimed
WO-2023019983-A1 NUCLEIC ACID FLUORESCENT DYE AND PREPARATION AND APPLICATION THEREOF 四川大学 2023-02-23 WO claimed
CN-114409582-A Method for preparing peroxyacetic acid and improving stability of peroxyacetic acid by adopting heterogeneous catalyst 兰州助剂厂有限责任公司 2022-04-29 CN claimed
CN-113583467-B Nucleic acid fluorescent dye and preparation and application thereof 四川大学 2022-04-26 CN claimed
CN-113686943-A Multifunctional nucleic acid dye and preparation method and application thereof 苏州优逸兰迪生物科技有限公司 2021-11-23 CN claimed
CN-113583467-A Nucleic acid fluorescent dye and preparation and application thereof 四川大学 2021-11-02 CN claimed
CN-111349091-B Fluorescent dye and preparation method and application thereof 北京富百科生物技术有限公司 2021-09-07 CN claimed
CN-111349091-A Novel fluorescent dye and preparation method and application thereof 北京富百科生物技术有限公司 2020-06-30 CN claimed
US-20190315770-A1 COMPOSITION FOR HARDENING SOFT TISSUE SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2019-10-17 US claimed
CN-102797043-A Medicinal molecular fragment library and construction method thereof CBB NETWORK CO LTD 2012-11-28 CN claimed
US-7252690-B2 Fuel composition EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-08-07 US claimed
EP-1246895-B1 FUEL COMPOSITION EXXONMOBIL RES & ENG CO (US) 2003-10-01 EP claimed
US-20030154648-A1 Fuel composition EXXONMOBIL RESEARCH & ENGINEERING CO. 2003-08-21 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0118685-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-19 EP claimed
EP-0117412-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-05 EP claimed
US-3994733-A CYANINE DYES, A BENZOTHIAZOLE, OR BENZOTHIAZOLONE, OR NAPHTHOTHIAZOLE, OR NAPHTHOTHIAZOLONE, OR A QUINOLONE FUJI PHOTO FILM CO., LTD. (JA) 1976-11-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315770-A1 COMPOSITION FOR HARDENING SOFT TISSUE PNLIP, AMY2A, RNASE1 CYP1A2 4782/4885BACE1 4505/4885ALDH1A1 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.