SCHEMBL870322

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870854	0.90	SYK (0.45)	DHODHCTSVCTSLHNF4AGSK3B
	SCHEMBL15636037	0.88	DHODH (0.58)	DHODHGSK3BGSK3ASMN1; SMN2GAA
	SCHEMBL15638933	0.85	DHODH (0.64)	DHODHGSK3BGSK3ASMN1; SMN2GAA
	SCHEMBL4770418	0.79	DHODH (0.49)	DHODHGSK3BGSK3ASMN1; SMN2GAA
	SCHEMBL15635777	0.79	LMNA (0.58)	DHODHGSK3BGSK3AMEN1KMT2A
	SCHEMBL870223	0.78	DHODH (0.53)	DHODHGSK3BMEN1KMT2AAURKA
	SCHEMBL17110947	0.78	SYK (0.51)	DHODHGSK3BGSK3ASMN1; SMN2RAB9A
	SCHEMBL871472	0.77	ERBB2 (0.60)	SMN1; SMN2RAB9AMEN1KMT2AALDH1A1
	SCHEMBL870804	0.76	KDM4E (0.55)	SMN1; SMN2GAAMEN1KMT2AALDH1A1
	SCHEMBL9128053	0.76	MAPT (0.53)	DHODHSMN1; SMN2AURKACDC7MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.