SCHEMBL870854

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870322	0.90	DHODH (0.51)	SYKDHODHMEN1KMT2ALMNA
	SCHEMBL15636037	0.86	DHODH (0.58)	SYKCYP1A2DHODHMEN1KMT2A
	SCHEMBL15635777	0.84	LMNA (0.58)	CYP1A2DHODHMEN1KMT2ALMNA
	SCHEMBL870223	0.84	DHODH (0.53)	CYP1A2DHODHMEN1KMT2ALMNA
	SCHEMBL869587	0.81	DHODH (0.46)	SYKCYP1A2DHODHMEN1KMT2A
	SCHEMBL17110905	0.79	AKR1C3 (0.55)	CYP1A2MEN1KMT2APKMALDH1A1
	SCHEMBL17110898	0.78	MEN1 (0.68)	SYKCYP1A2DHODHMEN1KMT2A
	SCHEMBL17363188	0.78	SYK (0.56)	SYKMEN1KMT2AALDH1A1CDC7
	SCHEMBL4874399	0.78	MEN1 (0.49)	CYP1A2DHODHMEN1KMT2ALMNA
	SCHEMBL15638933	0.77	DHODH (0.64)	DHODHMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.