Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 3/20 | 0.58 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.58 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.58 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29892720 | 1.00 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8L3MBTL1 | |
| SCHEMBL28309931 | 0.86 | L3MBTL1 (0.55) | ABCC9ABCC8KCNJ11KCNJ8L3MBTL1 | |
| SCHEMBL9169544 | 0.83 | ABCC9 (0.62) | ABCC9ABCC8KCNJ11KCNJ8L3MBTL1 | |
| SCHEMBL14088932 | 0.82 | KDM5A (0.62) | L3MBTL1TDP1PTGS2MAPTTSHR | |
| SCHEMBL11267256 | 0.81 | PRKCI (0.65) | L3MBTL1ATMTDP1MAPTTSHR | |
| SCHEMBL9470621 | 0.80 | L3MBTL1 (0.48) | ABCC9ABCC8KCNJ11KCNJ8L3MBTL1 | |
| SCHEMBL28409662 | 0.78 | MEN1 (0.72) | L3MBTL1ATMTDP1CNR2PTGS1 | |
| SCHEMBL1108312 | 0.78 | PRKCI (0.65) | MAPTKMT2ARAB9ANPC1 | |
| SCHEMBL31257839 | 0.77 | L3MBTL1 (0.64) | L3MBTL1ATMTDP1CNR2PTGS1 | |
| SCHEMBL142204 | 0.77 | L3MBTL1 (0.64) | L3MBTL1ATMTDP1CNR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |