Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787213 | 0.84 | ALDH1A1 (0.50) | PRKCIMAPK1PBRM1MAPTGAA | |
| SCHEMBL28309931 | 0.84 | L3MBTL1 (0.55) | PBRM1MAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL11789120 | 0.84 | ALDH1A1 (0.58) | PRKCIMAPK1PBRM1MAPTGAA | |
| SCHEMBL1067119 | 0.82 | PRKCI (0.73) | PRKCIMAPTGAAALDH1A1KDM4E | |
| SCHEMBL4286847 | 0.82 | GAA (0.77) | MAPK1PBRM1MAPTGAAMAPK13 | |
| SCHEMBL8703248 | 0.81 | ABCC9 (0.58) | MAPTGAAMAPK13MAPK12MAPK11 | |
| SCHEMBL29892720 | 0.81 | ABCC9 (0.58) | MAPTGAAMAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL18691959 | 0.81 | PRKCI (0.71) | PRKCIMAPTGAAALDH1A1KDM4E | |
| SCHEMBL11803700 | 0.80 | ALDH1A1 (0.61) | MAPK1PBRM1MAPTGAAMAPK13 | |
| SCHEMBL11788299 | 0.80 | ALDH1A1 (0.61) | MAPK1MAPTGAAMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |