Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CALML3 | P27482 | 1/20 | 0.45 |
| ▸ | SDHA | P31040 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871678 | 1.00 | MAOA (0.46) | MAOAABCB11MAOBLMNAPTGS1 | |
| SCHEMBL5707298 | 0.91 | ABCB11 (0.45) | MAOAABCB11MAOBLMNAPTGS1 | |
| SCHEMBL5707296 | 0.91 | ABCB11 (0.45) | MAOAABCB11MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1176889 | 0.90 | ABCB11 (0.45) | MAOAABCB11MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL1176888 | 0.90 | ABCB11 (0.45) | MAOAABCB11MAOBLMNAPTGS1 | |
| SCHEMBL9028107 | 0.89 | ABCB11 (0.44) | MAOAABCB11MAOBLMNAPTGS1 | |
| SCHEMBL10196083 | 0.88 | LMNA (0.43) | MAOALMNAF10 | |
| SCHEMBL8871159 | 0.87 | F10 (0.52) | MAOAABCB11MAOBLMNAPTGS1 | |
| SCHEMBL8701633 | 0.87 | F10 (0.52) | MAOAABCB11MAOBLMNAPTGS1 | |
| SCHEMBL9028665 | 0.86 | MAOA (0.43) | MAOAABCB11MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843967-A | 6-membered nitrogen-containing heteroaryl-oxazolidinones | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |