Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753967 | 0.65 | PTGS1 (0.33) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6783633 | 0.61 | KEAP1 (0.52) | HDAC6L3MBTL1KDM4EHPGDLMNA | |
| SCHEMBL15670597 | 0.61 | KDM4E (0.53) | MAPTKDM4EALDH1A1HSD17B10HTT | |
| SCHEMBL8825555 | 0.61 | P4HTM (0.49) | HDAC6L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL7650615 | 0.61 | HDAC6 (0.62) | HDAC6L3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL7829888 | 0.60 | HTT (0.53) | KDM4EALDH1A1HPGDTP53POLB | |
| SCHEMBL8377547 | 0.59 | KMT2A (0.44) | KDM4EALDH1A1TP53HSD17B10HTT | |
| SCHEMBL14639439 | 0.59 | KDM4E (0.59) | HDAC6L3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4012673 | 0.58 | KEAP1 (0.52) | HDAC6KDM4EALDH1A1KEAP1FFAR1 | |
| SCHEMBL7450221 | 0.56 | HDAC6 (0.65) | HDAC6L3MBTL1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721223-A | ANTIISCHEMIC AGENTS, ANALGESICS | HANSEN JR DONALD W (US) | 1998-02-24 | — | — | US | disclosed |
| US-5464843-A | ANTICONVULSANTS, ANALGESICS | G.D. SEARLE & CO. (US) | 1995-11-07 | — | — | US | disclosed |