Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150684 | 0.73 | KDM1A (0.43) | HDAC9KDM1ASIGMAR1EBPCASP6 | |
| SCHEMBL2771012 | 0.73 | KDM1A (0.43) | HDAC9KDM1ASIGMAR1EBPCASP6 | |
| SCHEMBL2766163 | 0.73 | KDM1A (0.43) | HDAC9KDM1ASIGMAR1EBPCASP6 | |
| SCHEMBL11286184 | 0.69 | KDM1A (0.42) | KDM5AKDM4CKDM5BKIF11HDAC9 | |
| Bicarbonate SCHEMBL28494150 | 0.68 | KDM1A (0.51) | KDM5AKDM4CKDM5BHDAC9KDM1A | |
| SCHEMBL15673547 | 0.68 | NR3C1 (0.44) | KDM5AKDM4CKDM5BHDAC9KDM1A | |
| SCHEMBL8711235 | 0.68 | KMT2A (0.37) | KIF11MEN1KMT2A | |
| SCHEMBL14214939 | 0.68 | OPRM1 (0.51) | HDAC9SIGMAR1 | |
| SCHEMBL9183854 | 0.67 | KDM1A (0.46) | KDM1ASIGMAR1EBPMEN1KMT2A | |
| SCHEMBL4851505 | 0.67 | KDM1A (0.50) | KDM5AKDM4CKDM5BHDAC9KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |