Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703449 | 0.72 | LMNA (0.37) | KMT2AMEN1KIF11HTR1AADRA1A | |
| SCHEMBL8710208 | 0.68 | BRD4 (0.48) | KMT2AMEN1CYP1A2POLBTSHR | |
| SCHEMBL8704259 | 0.68 | KDM5A (0.42) | KMT2AMEN1KIF11 | |
| SCHEMBL2512448 | 0.65 | TSHR (0.42) | POLBTSHROPRM1OPRL1LMNA | |
| SCHEMBL21219221 | 0.63 | THRB (0.44) | KMT2AMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL29506875 | 0.63 | THRB (0.44) | KMT2AMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL6070188 | 0.62 | ALDH1A1 (0.61) | KMT2AMEN1TSHROPRM1KIF11 | |
| SCHEMBL23553895 | 0.62 | CA12 (0.42) | TSHRTDP1OPRM1OPRK1OPRL1 | |
| SCHEMBL30024606 | 0.62 | CA12 (0.42) | TSHRTDP1OPRM1OPRK1OPRL1 | |
| SCHEMBL30807380 | 0.62 | OPRM1 (0.56) | TSHRTDP1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |