Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710011 | 1.00 | LMNA (0.33) | LMNAHTTMAPTMAOBNOTUM | |
| SCHEMBL3000591 | 0.72 | BRD4 (0.41) | HTTMAOBMAOAALDH1A1 | |
| SCHEMBL28922481 | 0.64 | — | — | |
| SCHEMBL24426420 | 0.64 | KDM1A (0.34) | LMNAHTTMAPTMAOBMAOA | |
| SCHEMBL15810954 | 0.64 | HTT (0.31) | HTTMAOBALDH1A1KDM1A | |
| SCHEMBL17382164 | 0.63 | ALDH1A1 (0.44) | LMNAMAOBMAOAALDH1A1KDM1A | |
| SCHEMBL24355003 | 0.63 | HTT (0.36) | HTTMAPTALDH1A1HSD17B10 | |
| SCHEMBL8738128 | 0.61 | MAPT (0.54) | LMNAMAPTMAOBMAOAALDH1A1 | |
| SCHEMBL18887607 | 0.61 | MAOA (0.50) | LMNAHTTMAPTMAOBMAOA | |
| SCHEMBL27549602 | 0.60 | ALDH1A1 (0.35) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795887-A | Method of inducing cholecystokinin agonist activity using 1,4- Benzodiazepine compounds | GLAXO WELLCOME INC. (US) | 1998-08-18 | — | — | US | disclosed |