Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471038 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2HPGDGAAHTT | |
| SCHEMBL9037517 | 0.80 | LMNA (0.62) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10683659 | 0.75 | HSD17B10 (0.47) | ALDH1A1SMN1; SMN2HPGDKMT2AMAPT | |
| SCHEMBL11636916 | 0.73 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2HPGDGAAMTNR1B | |
| SCHEMBL6691251 | 0.73 | ACHE (0.47) | ALDH1A1SMN1; SMN2HPGDGAAHTT | |
| SCHEMBL20411799 | 0.73 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL9037525 | 0.73 | MEN1 (0.46) | ALDH1A1SMN1; SMN2GAAKMT2AMAPT | |
| SCHEMBL9037210 | 0.72 | GAA (0.54) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL13129135 | 0.71 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HPGDGAAPTPN1 | |
| SCHEMBL11263218 | 0.71 | CYP3A4 (0.49) | ALDH1A1HPGDKMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731340-A | DIETETICS; ANTIDIABETIC AGENTS | SANOFI (FR) | 1998-03-24 | — | — | US | disclosed |
| EP-0697403-A1 | Derivatives of glycinamides as cholecystokinin receptor agonists | SANOFI (FR) | 1996-02-21 | — | — | EP | disclosed |