SCHEMBL56657

SCHEMBL56657

Cc1ccc2c(c1)C(=O)CCS2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.64
ELOC Q15369 1/20 0.64
ELOB Q15370 1/20 0.64
KDM4E B2RXH2 5/20 0.53
ALDH1A1 P00352 4/20 0.53
HTT P42858 2/20 0.50
MAPT P10636 2/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
CTSL P07711 1/20 0.48
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.40
EPHX2 P34913 1/20 0.39
PARP1 P09874 1/20 0.39
PARP10 Q53GL7 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2775772 0.85 KDM4E (0.63) VHLELOCELOBKDM4EALDH1A1
SCHEMBL10054228 0.81 EPHX2 (0.49) VHLELOCELOBKDM4EALDH1A1
SCHEMBL13204570 0.78 CTSL (0.48) VHLELOCELOBKDM4EALDH1A1
SCHEMBL10720643 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL29595944 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL6592045 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL69249 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL69544 0.78 VHL (1.00) VHLELOCELOBKDM4EALDH1A1
SCHEMBL69545 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1
SCHEMBL12743 0.78 VHL (0.64) VHLELOCELOBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
EP-3950856-A1 PHOTOCURABLE INK COMPOSITION AND METHOD FOR IMAGE RECORDING FUJIFILM Corporation (JP) 2022-02-09 EP disclosed
US-20210395549-A1 PHOTOCURABLE INK COMPOSITION AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
US-20200199385-A1 ACTIVE ENERGY RAY CURABLE-TYPE INK JET INK, LIGHT SHIELDING FILM, AND METHOD OF MANUFACTURING LIGHT SHIELDING FILM FUJIFILM CORPORATION (JP) 2020-06-25 US disclosed
EP-2502967-B1 Ink composition FUJIFILM SPECIALITY INK SYSTEMS LTD (GB) 2019-08-21 EP disclosed
EP-2412768-B1 Inkjet ink composition, inkjet recording method, and printed material FUJIFILM CORP (JP) 2019-01-23 EP disclosed
US-9878560-B2 Inkjet recording method using nozzle arrays and printed material obtained by the inkjet recording method FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1944173-A1 Ink composition and inkjet recording method using the same FUJIFILM Corporation (JP) 2008-07-16 EP disclosed
US-RE39679-E1 Substituted heterocycle fused gamma-carbolines BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2007-06-05 US disclosed
US-6713471-B1 SUCH AS TERT-BUTYL-1-METHYL-6,7,9,12-TETRAHYDRO-5H-PYRIDO-(4,3-B)(1,4) THIAZEPINO(2,3,4-HI)INDOLE-11(10H)-CARBOXYLATE; SEROTONIN AGONISTS AND ANTAGONISTS; CENTRAL NERVOUS SYSTEM DISORDERS BRISTOL-MYERS SQUIBB PHARMA COMPANY 2004-03-30 US disclosed
EP-0212428-B1 DIHYDROBENZO/B /THIOPHENES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS ANTIFUNGALS SCHERING CORPORATION (US) 1990-06-06 EP disclosed
US-4731364-A Dihydrobenzo(B)thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1988-03-15 US disclosed
EP-0212428-A1 Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1987-03-04 EP disclosed
US-4105778-A ANTIALLERGENS, BACTERICIDES, FUNGICIDES AYERST, MCKENNA & HARRISON, LTD. (CA) 1978-08-08 US disclosed
US-4060619-A ANTIALLERGY, MICROBIOCIDE AYERST MCKENNA AND HARRISON LTD. (CA) 1977-11-29 US disclosed