Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.71 |
| ▸ | BCHE | P06276 | 5/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101439 | 0.84 | CHRM2 (0.73) | CHRM2BCHEACHECHRM1MAOB | |
| SCHEMBL7416019 | 0.83 | CHRM2 (0.71) | CHRM2BCHEACHECHRM1MAOB | |
| SCHEMBL19080598 | 0.81 | CHRM2 (0.72) | CHRM2BCHEACHECHRM1MAOB | |
| SCHEMBL4514454 | 0.80 | CHRM2 (0.67) | CHRM2BCHEACHECHRM1MAOB | |
| SCHEMBL27871240 | 0.80 | ACHE (0.65) | BCHEACHEMAOBAPP | |
| SCHEMBL19091136 | 0.80 | CHRM2 (0.70) | CHRM2BCHEACHECHRM1MAOB | |
| SCHEMBL7960394 | 0.79 | CHRM2 (0.45) | CHRM2BCHEACHECHRM1APP | |
| Hydrochloric Acid SCHEMBL7597748 | 0.78 | CHRM2 (0.44) | CHRM2BCHEACHECHRM1APP | |
| SCHEMBL13706633 | 0.78 | CHRM2 (0.82) | CHRM2BCHEACHECHRM1MAOB | |
| SCHEMBL735118 | 0.77 | SLC6A4 (0.68) | CHRM2CHRM1AOC3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |