Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.77 |
| ▸ | CES1 | P23141 | 5/20 | 0.77 |
| ▸ | IDO1 | P14902 | 2/20 | 0.60 |
| ▸ | TDO2 | P48775 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionamide SCHEMBL8706214 | 0.89 | TGM2 (0.71) | TGM2CES1IDO1TDO2MAOA | |
| SCHEMBL29506317 | 0.88 | TGM2 (1.00) | TGM2CES1IDO1TDO2MAOA | |
| SCHEMBL134453 | 0.88 | TGM2 (1.00) | TGM2CES1IDO1TDO2MAOA | |
| SCHEMBL1462357 | 0.86 | TGM2 (0.96) | TGM2CES1IDO1TDO2MAOA | |
| Methane SCHEMBL27958656 | 0.86 | TGM2 (0.96) | TGM2CES1IDO1TDO2MAOA | |
| Nitrogen SCHEMBL29155961 | 0.84 | TGM2 (0.92) | TGM2CES1IDO1TDO2MAOA | |
| Acetamide SCHEMBL27380996 | 0.83 | ROS1 (0.56) | TGM2CES1MAOAMAOBLRRK2 | |
| 5-Fluoroisatin SCHEMBL8708925 | 0.81 | MAOB (0.51) | TGM2CES1MAOAMAOBLRRK2 | |
| Phenol SCHEMBL674629 | 0.79 | CES1 (0.75) | TGM2CES1IDO1TDO2MAOA | |
| 5-Fluoroisatin SCHEMBL11132105 | 0.79 | CES1 (0.80) | TGM2CES1IDO1TDO2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833638-A1 | USE OF IMIDAZO 1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |