Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.96 |
| ▸ | CES1 | P23141 | 5/20 | 0.96 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | MAOB | P27338 | 4/20 | 0.65 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.54 |
| ▸ | PPOX | P50336 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134453 | 0.98 | TGM2 (1.00) | TGM2CES1MAOAMAOBCHEK1 | |
| SCHEMBL29506317 | 0.98 | TGM2 (1.00) | TGM2CES1MAOAMAOBCHEK1 | |
| SCHEMBL1462357 | 0.96 | TGM2 (0.96) | TGM2CES1MAOAMAOBCHEK1 | |
| Nitrogen SCHEMBL29155961 | 0.94 | TGM2 (0.92) | TGM2CES1MAOAMAOBCHEK1 | |
| 5-Fluoroisatin SCHEMBL11132105 | 0.88 | CES1 (0.80) | TGM2CES1MAOAMAOBCHEK1 | |
| Acetamide SCHEMBL8705155 | 0.86 | TGM2 (0.77) | TGM2CES1MAOAMAOBCHEK1 | |
| SCHEMBL31139641 | 0.85 | CES1 (0.77) | TGM2CES1MAOAMAOBCHEK1 | |
| Phenol SCHEMBL674629 | 0.85 | CES1 (0.75) | TGM2CES1MAOAMAOBCHEK1 | |
| SCHEMBL4370977 | 0.83 | CES1 (0.73) | TGM2CES1MAOAMAOBCHEK1 | |
| N-Methylpiperidine SCHEMBL4627711 | 0.82 | CES1 (0.71) | TGM2CES1MAOAMAOBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384769-B | Synthetic method of R-configuration 3-substituted-3-hydroxy oxindole compound | 陕西师范大学 | 2020-12-22 | — | — | CN | claimed |
| CN-109384769-B | Synthetic method of R-configuration 3-substituted-3-hydroxy oxindole compound | 陕西师范大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-109384769-A | A kind of synthetic method of R configuration 3- substitution -3- hydroxyl oxidized indole compounds | 陕西师范大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-106220641-B | Containing the indoles volution compound and the preparation method and application thereof for more creating blue hydrocarbon Azulene structure | 渤海大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-106188075-B | Indoles volution compound and the preparation method and application thereof | 牡丹江师范学院 | 2018-10-12 | — | — | CN | disclosed |
| CN-104557957-B | Synthetic method of spiro-oxoindole ethylene oxide derivative | 华东师范大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-106220641-A | Indole volution compound containing the blue hydrocarbon structure of more wound and preparation method and application | 渤海大学 | 2016-12-14 | — | — | CN | disclosed |
| CN-106188075-A | New indole volution compound and preparation method and application | 牡丹江师范学院 | 2016-12-07 | — | — | CN | disclosed |
| CN-103788102-B | A kind of synthetic method of volution Oxoindole butenolide compound | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-103788102-A | Synthesis method for spirally-epoxidized indole butenolide compound | UNIV CHINA PHARMA | 2014-05-14 | — | — | CN | disclosed |