Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TOP2A | P11388 | 3/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404787 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL10108013 | 0.98 | ALDH1A1 (0.70) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL5009825 | 0.94 | TOP2A (0.64) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL537869 | 0.87 | TOP2A (0.62) | ALDH1A1TOP2ALTA4HCYP4F2CYP4A11 | |
| SCHEMBL380632 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TOP2ANAMPTLTA4HPDE5A | |
| SCHEMBL1472555 | 0.86 | LMNA (0.66) | ALDH1A1HDAC3HDAC1HDAC2NCOR2 | |
| Hydrochloric Acid SCHEMBL7130173 | 0.86 | TOP2A (0.61) | ALDH1A1TOP2ALTA4HCYP4F2CYP4A11 | |
| SCHEMBL6829473 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL11324004 | 0.85 | TOP2A (0.59) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL19361381 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849732-A | Phenol compound having antioxidative activity and the process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |