Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | TOP2A | P11388 | 3/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705157 | 0.98 | ALDH1A1 (0.68) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL11404787 | 0.98 | ALDH1A1 (0.68) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL5009825 | 0.95 | TOP2A (0.64) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL537869 | 0.89 | TOP2A (0.62) | ALDH1A1TOP2ALTA4HCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL7130173 | 0.87 | TOP2A (0.61) | ALDH1A1TOP2ALTA4HCYP4F2CYP4A11 | |
| SCHEMBL11324004 | 0.87 | TOP2A (0.59) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL7714032 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL380632 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TOP2ANAMPTLTA4HPDE5A | |
| SCHEMBL10107952 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TOP2ANAMPTLTA4HCYP4F2 | |
| SCHEMBL1472555 | 0.84 | LMNA (0.66) | ALDH1A1LMNAMAPTHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466161-B2 | Hydroxamate derivative, a production method for the same, and a pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-06-18 | — | — | US | disclosed |
| US-20120028963-A1 | NOVEL HYDROXAMATE DERIVATIVE, A PRODUCTION METHOD FOR THE SAME, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028963-A1 | NOVEL HYDROXAMATE DERIVATIVE, A PRODUCTION METHOD FOR THE SAME, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HAAO, HPD, HCAR2 | ALDH1A1 910/4885TOP2A 2264/4885NAMPT 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.