Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.58 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010838 | 0.86 | ALDH3A1 (0.64) | ALDH3A1ALDH1A1ALDH2CUL4ACA12 | |
| SCHEMBL8706219 | 0.85 | ALDH3A1 (0.59) | ALDH3A1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL8708926 | 0.82 | PARK7 (0.63) | ALDH3A1ALDH1A1CUL4ACA12CA1 | |
| SCHEMBL11959135 | 0.81 | ALDH1A1 (0.56) | ALDH3A1ALDH1A1ALDH2CUL4APOLB | |
| SCHEMBL4624033 | 0.81 | ALDH3A1 (0.65) | ALDH3A1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL27703276 | 0.79 | ALDH1A1 (0.76) | ALDH3A1ALDH1A1ALDH2CUL4APOLB | |
| SCHEMBL4625293 | 0.78 | ALDH3A1 (0.65) | ALDH3A1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL11959136 | 0.78 | ALDH1A1 (0.53) | ALDH3A1ALDH1A1ALDH2CUL4APOLB | |
| SCHEMBL6275037 | 0.78 | PARK7 (0.66) | ALDH3A1ALDH1A1ALDH2CA12CA1 | |
| SCHEMBL32677715 | 0.78 | PARK7 (0.66) | ALDH3A1ALDH1A1ALDH2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833638-A1 | USE OF IMIDAZO 1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |