Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361649 | 0.85 | ADRB1 (0.61) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL2156292 | 0.84 | ADRB1 (0.59) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL7711565 | 0.84 | ADRB1 (0.59) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| SCHEMBL8257139 | 0.82 | ABCB1 (0.54) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| SCHEMBL1107020 | 0.79 | CHRNB2 (0.46) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| SCHEMBL2292016 | 0.78 | FYN (0.58) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| SCHEMBL1600775 | 0.78 | ADRB1 (0.56) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| SCHEMBL8257463 | 0.78 | ABCB1 (0.53) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| SCHEMBL19579582 | 0.78 | ACVR1 (0.51) | HTR1AHTR7ADRB1HTR3EHTR3B | |
| SCHEMBL873466 | 0.77 | ADRB1 (0.51) | HTR1AHTR7ADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |