Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.61 |
| ▸ | HTR3A | P46098 | 4/20 | 0.61 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.61 |
| ▸ | HTR3B | O95264 | 3/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7711565 | 0.98 | ADRB1 (0.59) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL2156292 | 0.98 | ADRB1 (0.59) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL873466 | 0.88 | ADRB1 (0.51) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8106637 | 0.88 | CHRNB2 (0.52) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL10208374 | 0.86 | ADRB1 (0.67) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL10154835 | 0.86 | ADRB1 (0.57) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL27403145 | 0.86 | ADRB1 (0.67) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8705185 | 0.85 | HTR1A (0.49) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL14922727 | 0.85 | CHRNB2 (0.52) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL874294 | 0.85 | PDE4B (0.53) | ADRB1HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112831206-B | Inorganic oxide dispersion with controllable water content and preparation method thereof | 凯斯科技股份有限公司 | 2022-12-30 | — | — | CN | claimed |
| WO-2024145435-A2 | LIPID COMPOSITIONS AND METHODS FOR DELIVERY TO IMMUNE CELLS | Life Technologies Corporation (US) | 2024-07-04 | — | — | WO | disclosed |
| US-20230181742-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2023-06-15 | — | — | US | disclosed |
| US-20230107757-A1 | POLY(BETA-AMINO ESTER)-CO-POLYETHYLENE GLYCOL (PEG-PBAE-PEG) POLYMERS FOR GENE AND DRUG DELIVERY | THE JOHNS HOPKINS UNIVERSTY | 2023-04-06 | — | — | US | disclosed |
| CN-112831206-B | Inorganic oxide dispersion with controllable water content and preparation method thereof | 凯斯科技股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| US-20210252154-A1 | MULTICOMPONENT DEGRADABLE CATIONIC POLYMERS | THE JOHNS HOPKINS UNIVERISTY | 2021-08-19 | — | — | US | disclosed |
| CN-113214102-A | Amine-containing transfection reagents and methods of making and using same | 生命技术公司 | 2021-08-06 | — | — | CN | disclosed |
| US-20210220287-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | THE JOHNS HOPKINS UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| CN-108358812-B | Amine-containing transfection reagents and methods of making and using same | 生命技术公司 | 2021-05-11 | — | — | CN | disclosed |
| US-20210101875-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-08 | — | — | US | disclosed |
| EP-0185909-A1 | 5-Alkyl-1-phenyl-2-piperazino alkylpyrazolin-3-one compounds as well as processes and intermediates for their preparation and medicaments containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1986-07-02 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| US-4552878-A | ANTIDEPRESSANTS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1985-11-12 | — | — | US | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |
| US-4302588-A | 5-(3-SUBSTITUTED AMINO)-2-HYDROXY-PROPYLOXY)-8-HYDROXY OR ALKOXY-CARBOSTYRILS, ADRENERGIC BLOCKING AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-11-24 | — | — | US | disclosed |
| US-4289883-A | ADRENERGIC BLOCKING AGENTS OF EXCELLENT CARDIOSELECTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-15 | — | — | US | disclosed |
| US-4210753-A | TREATMENT OF CARDIAC DISORDERS AND CHRONIC LUNG DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-01 | — | — | US | disclosed |
| US-4176191-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1979-11-27 | — | — | US | disclosed |
| US-4145422-A | HYPOTENSIVES | ABBOTT LABORATORIES (US) | 1979-03-20 | — | — | US | disclosed |
| US-3948898-A | HYPOTENSIVES, SEDATIVES, ANTIARRHYTHMICS, BRADYCARDIACS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181742-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | SNRPA, NUDT21, SOAT2 | ADRB1 2390/4885HTR3A 2204/4885HTR3E 2058/4885 |
| US-20210101875-A1 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | PHOSPHO1, PNMT, AASDHPPT | ADRB1 893/4885HTR3A 3398/4885HTR3E 3747/4885 |
| US-20210252154-A1 | MULTICOMPONENT DEGRADABLE CATIONIC POLYMERS | PEF1, FIBP, PARN | ADRB1 4466/4885HTR3A 1018/4885HTR3E 1159/4885 |
| US-20230107757-A1 | POLY(BETA-AMINO ESTER)-CO-POLYETHYLENE GLYCOL (PEG-PBAE-PEG) POLYMERS FOR GENE AND DRUG DELIVERY | PBDC1, BCAT1, PBRM1 | ADRB1 2945/4885HTR3A 3882/4885HTR3E 1899/4885 |
| US-20210220287-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | ADRB1 3417/4885HTR3A 4048/4885HTR3E 3338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.