Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304735 | 0.87 | TBXAS1 (0.61) | TBXAS1ALDH1A1ABL1RIN1CYP11B1 | |
| SCHEMBL8307497 | 0.84 | ALDH1A1 (0.47) | TBXAS1ALDH1A1ABL1RIN1CYP11B1 | |
| SCHEMBL8705229 | 0.81 | ALDH1A1 (0.45) | TBXAS1ALDH1A1ABL1RIN1CYP11B1 | |
| SCHEMBL8304691 | 0.81 | TBXAS1 (0.57) | TBXAS1NAMPTAGTR2 | |
| SCHEMBL11487884 | 0.80 | CYP11B1 (0.56) | TBXAS1ALDH1A1ABL1RIN1CYP11B1 | |
| SCHEMBL11474932 | 0.80 | TBXAS1 (0.67) | TBXAS1ALDH1A1ABL1RIN1CYP11B1 | |
| SCHEMBL8707667 | 0.78 | CYP4F2 (0.42) | TBXAS1NAMPT | |
| SCHEMBL8304913 | 0.76 | TBXAS1 (0.45) | TBXAS1ALDH1A1ABL1RIN1CYP11B1 | |
| SCHEMBL8304690 | 0.76 | TBXAS1 (0.78) | TBXAS1ALDH1A1NAMPTAGTR2 | |
| SCHEMBL8702346 | 0.75 | TBXAS1 (0.49) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705523-A | THROMBOXANE A2 SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-01-06 | — | — | US | disclosed |