Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 3/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | TDP2 | O95551 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.36 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728861 | 0.75 | MAPT (0.37) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9728856 | 0.75 | MAPT (0.37) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9728849 | 0.75 | MAPT (0.37) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL26924676 | 0.71 | TDP2 (0.32) | TDP1TDP2NSD2PAX8MEN1 | |
| SCHEMBL18921 | 0.71 | TDP2 (0.32) | TDP1TDP2NSD2PAX8MEN1 | |
| Hydrochloric Acid SCHEMBL6025175 | 0.70 | TDP2 (0.31) | TDP1TDP2NSD2PAX8MEN1 | |
| SCHEMBL2230292 | 0.68 | MAPT (0.40) | S100A4CDC25BTDP1TDP2NSD2 | |
| SCHEMBL28978114 | 0.68 | S100A4 (0.34) | S100A4CDC25BTDP1TDP2NSD2 | |
| SCHEMBL670066 | 0.68 | BRD4 (0.36) | S100A4CDC25BTDP1TDP2NSD2 | |
| SCHEMBL4074635 | 0.66 | MAPT (0.39) | S100A4CDC25BTDP1TDP2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014071316-A1 | IN SILICO IDENTIFICATION OF CANCER MOLECULAR SIGNALING PATHWAYS AND DRUG CANDIDATES | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2014-05-08 | — | — | WO | disclosed |
| US-5733918-A | ANTITUMOR AGENT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| US-5710162-A | ANTITUMOR AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |