Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700453 | 0.91 | RBP4 (0.56) | MAPTLMNATSHRSMN1; SMN2RBP4 | |
| SCHEMBL8705266 | 0.88 | KMT2A (0.52) | MAPTLMNATSHRSMN1; SMN2NPSR1 | |
| SCHEMBL8699871 | 0.82 | GAA (0.48) | MAPTLMNATSHRSMN1; SMN2RBP4 | |
| SCHEMBL8704433 | 0.81 | MAPT (0.48) | MAPTSMN1; SMN2RBP4HTTPANK3 | |
| SCHEMBL8699435 | 0.81 | RBP4 (0.49) | MAPTLMNATSHRRBP4MAPK1 | |
| SCHEMBL8704931 | 0.81 | RBP4 (0.57) | MAPTLMNATSHRSMN1; SMN2RBP4 | |
| SCHEMBL8703619 | 0.81 | GAA (0.48) | MAPTLMNATSHRSMN1; SMN2RBP4 | |
| SCHEMBL8702850 | 0.81 | PANK3 (0.56) | MAPTLMNATSHRSMN1; SMN2NPSR1 | |
| SCHEMBL8699119 | 0.81 | KDM4E (0.55) | MAPTLMNARAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8699373 | 0.81 | MAPT (0.47) | MAPTRBP4HTTPANK3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |