Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 1.00 |
| ▸ | DRD4 | P21917 | 16/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706290 | 0.90 | DRD2 (1.00) | DRD2DRD4HTR2ASIGMAR1MCHR1 | |
| SCHEMBL8707354 | 0.90 | DRD2 (1.00) | DRD2DRD4HTR2ASIGMAR1MCHR1 | |
| SCHEMBL8711822 | 0.87 | DRD2 (0.85) | DRD2DRD4HTR2AMCHR1NAMPT | |
| SCHEMBL8706523 | 0.87 | DRD2 (1.00) | DRD2DRD4HTR2ANAMPT | |
| SCHEMBL8706273 | 0.87 | DRD2 (0.89) | DRD2DRD4HTR2ANAMPT | |
| SCHEMBL8711087 | 0.86 | DRD2 (1.00) | DRD2DRD4HTR2ASIGMAR1MCHR1 | |
| SCHEMBL7694199 | 0.85 | DRD2 (0.85) | DRD2DRD4HTR2ASIGMAR1MCHR1 | |
| SCHEMBL7694198 | 0.85 | DRD2 (0.85) | DRD2DRD4HTR2ASIGMAR1MCHR1 | |
| SCHEMBL8712569 | 0.84 | DRD4 (1.00) | DRD2DRD4HTR2A | |
| SCHEMBL8712702 | 0.84 | DRD2 (1.00) | DRD2DRD4HTR2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037064-A1 | BENZAMIDES HAVING DOPAMINE D4 RECEPTOR AFFINITY | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-27 | — | — | WO | disclosed |