Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496624 | 0.87 | SLC6A3 (0.50) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8695178 | 0.83 | TACR2 (0.43) | SLC6A3 | |
| SCHEMBL6579345 | 0.82 | SLC6A3 (0.45) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL9053699 | 0.81 | SLC6A3 (0.44) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8393742 | 0.81 | SLC6A3 (0.44) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6577520 | 0.81 | SLC6A3 (0.44) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL5858706 | 0.80 | SLC6A3 (0.42) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8391383 | 0.79 | SLC6A3 (0.42) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL4630703 | 0.79 | SLC6A3 (0.45) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8972640 | 0.79 | SLC6A3 (0.48) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018762-A1 | NEW DERIVATIVES OF DIVERSELY SUBSTITUTED CYCLICAL AMIDE SELECTIVE ANTAGONISTS OF THE HUMAN RECEPTOR NK3, PROCESS FOR OBTAINING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1998-05-07 | — | — | WO | disclosed |