Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858706 | 0.83 | SLC6A3 (0.42) | SLC6A3KDM4CSLC6A2SLC6A4MEN1 | |
| SCHEMBL6579345 | 0.83 | SLC6A3 (0.45) | SLC6A3KDM4CSLC6A2SLC6A4MEN1 | |
| SCHEMBL6577520 | 0.82 | SLC6A3 (0.44) | SLC6A3KDM4CSLC6A2SLC6A4MEN1 | |
| SCHEMBL4630703 | 0.82 | SLC6A3 (0.45) | SLC6A3KDM4CSLC6A2SLC6A4MEN1 | |
| SCHEMBL8782641 | 0.81 | SLC6A3 (0.46) | SLC6A3KDM4CSLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL8706751 | 0.81 | SLC6A3 (0.48) | SLC6A3KDM4CSLC6A2SLC6A4MEN1 | |
| Hydrochloric Acid SCHEMBL8369516 | 0.81 | SLC6A3 (0.45) | SLC6A3KDM4CSLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL7305306 | 0.79 | SLC6A3 (0.41) | SLC6A3KDM4CSLC6A2SLC6A4MEN1 | |
| SCHEMBL4631262 | 0.78 | SLC6A3 (0.43) | SLC6A3KDM4CSLC6A2SLC6A4MEN1 | |
| SCHEMBL7496624 | 0.78 | SLC6A3 (0.50) | SLC6A3SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726893-A1 | NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA | ZENECA LIMITED (GB) | 1996-08-21 | — | — | EP | disclosed |