Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21854752 | 0.92 | F2 (0.46) | HTR2CPRCPTSHRKMT2APDK1 | |
| Trifluoroacetic Acid SCHEMBL28969098 | 0.90 | PRCP (0.61) | HTR2CPRCPSMN1; SMN2TSHRL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL21854716 | 0.88 | CTRB1 (0.52) | HTR2CPRCPTSHRL3MBTL1KMT2A | |
| Trifluoroacetic Acid SCHEMBL21854670 | 0.88 | KDM4E (0.52) | HTR2CTSHRL3MBTL1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL30253251 | 0.88 | HTR2C (0.46) | HTR2CSMN1; SMN2TSHRL3MBTL1KMT2A | |
| SCHEMBL1257136 | 0.85 | HTR2C (0.50) | HTR2CPRCPSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL2439870 | 0.84 | TSHR (0.48) | HTR2CPRCPSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL2439873 | 0.84 | TSHR (0.48) | HTR2CPRCPSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL21854732 | 0.84 | HTR2C (0.51) | HTR2CPRCPSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL8707997 | 0.83 | NPSR1 (0.49) | HTR2CPRCPTSHRL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081917-A1 | ΒETA-CATENIN AND B-CELL LYMPHOMA 9 (BCL9) INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |