Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21879686 | 0.82 | LMNA (0.51) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL27724475 | 0.82 | LMNA (0.56) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL29262209 | 0.82 | LMNA (0.55) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL3783602 | 0.76 | ESR1 (0.43) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL338936 | 0.76 | DHODH (0.49) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL901570 | 0.76 | DHODH (0.53) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL25177897 | 0.75 | KDM4E (0.60) | LMNAKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL3082616 | 0.74 | LMNA (0.47) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL3446771 | 0.73 | LMNA (0.52) | LMNAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL2846662 | 0.73 | LMNA (0.52) | LMNAKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782577-A4 | ASYMMETRIC LIGANDS USEFUL FOR TRANSITION METAL CATALYZED BOND FORMING REACTIONS AND EPOXIDE REACTIONS THEREWITH | UNIV LELAND STANFORD JUNIOR (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0782577-A1 | ASYMMETRIC LIGANDS USEFUL FOR TRANSITION METAL CATALYZED BOND FORMING REACTIONS AND EPOXIDE REACTIONS THEREWITH | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009306-A1 | ASYMMETRIC LIGANDS USEFUL FOR TRANSITION METAL CATALYZED BOND FORMING REACTIONS AND EPOXIDE REACTIONS THEREWITH | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1996-03-28 | — | — | WO | disclosed |