Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934162 | 0.94 | NPC1 (0.39) | L3MBTL1SMN1; SMN2KDM4ENPC1TDP1 | |
| SCHEMBL7857665 | 0.82 | KDM4E (0.33) | L3MBTL1NPSR1KDM4ECYP1A2ALDH1A1 | |
| SCHEMBL71518 | 0.70 | NPSR1 (0.59) | L3MBTL1NPSR1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL29133980 | 0.69 | L3MBTL1 (0.41) | L3MBTL1NPSR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13482134 | 0.69 | TMPRSS15 (0.41) | L3MBTL1NPSR1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL1452596 | 0.68 | L3MBTL1 (0.44) | L3MBTL1NPSR1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10567090 | 0.68 | KMT2A (0.44) | L3MBTL1SMN1; SMN2KDM4ECYP1A2NPC1 | |
| SCHEMBL10565017 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13482930 | 0.68 | FFAR4 (0.41) | L3MBTL1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL29133916 | 0.67 | KMT2A (0.45) | L3MBTL1NPSR1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792767-A | TREATMENT OF BENIGN PROSTATIC HYPERTROPY | ABBOTT LABORATORIES (US) | 1998-08-11 | — | — | US | disclosed |