Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 9/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708786 | 0.88 | PDE4D (0.43) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL8707476 | 0.87 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8714452 | 0.86 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL8707002 | 0.85 | L3MBTL1 (0.41) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL8707692 | 0.81 | NR1H3 (0.53) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8707973 | 0.77 | L3MBTL1 (0.41) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL8711862 | 0.75 | NR1H2 (0.41) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL8707864 | 0.75 | PDE4B (0.53) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8712873 | 0.74 | PDE4B (0.52) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8711275 | 0.72 | RAB9A (0.57) | PDE4BPDE4DPDE4APDE4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |