Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709246 | 1.00 | REN (0.42) | RENKLK5BCHEMETAP2METAP1 | |
| SCHEMBL8711623 | 1.00 | REN (0.42) | RENKLK5BCHEMETAP2METAP1 | |
| SCHEMBL8712609 | 0.88 | REN (0.53) | RENKLK5ATMKMT2A | |
| SCHEMBL8712611 | 0.88 | REN (0.53) | RENKLK5ATMKMT2A | |
| SCHEMBL8712293 | 0.84 | REN (0.43) | RENKLK5 | |
| SCHEMBL8709818 | 0.84 | REN (0.43) | RENKLK5 | |
| SCHEMBL8709813 | 0.84 | REN (0.43) | RENKLK5 | |
| SCHEMBL8708800 | 0.84 | ATM (0.44) | KLK5ATM | |
| SCHEMBL8708798 | 0.84 | ATM (0.44) | KLK5ATM | |
| SCHEMBL6442715 | 0.79 | CTSD (0.51) | RENKLK5BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |