Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243070 | 0.86 | KMT2A (0.84) | MAPTALDH1A1KMT2AATMKDM4E | |
| SCHEMBL7362981 | 0.85 | MAPT (0.73) | MAPTALDH1A1KMT2AATMCRHBP | |
| SCHEMBL10959920 | 0.84 | MAPT (0.71) | MAPTALDH1A1KMT2AGAAHPGD | |
| SCHEMBL17087080 | 0.83 | MAPT (0.70) | MAPTALDH1A1KMT2AATMCRHBP | |
| SCHEMBL8605626 | 0.83 | MAPT (0.70) | MAPTALDH1A1KMT2AATMCRHBP | |
| SCHEMBL8706583 | 0.82 | HSD17B10 (0.71) | MAPTALDH1A1KMT2AGAAHPGD | |
| SCHEMBL527544 | 0.82 | KMT2A (0.71) | MAPTALDH1A1KMT2AHTTGAA | |
| SCHEMBL12736161 | 0.81 | MAPT (0.72) | MAPTALDH1A1KMT2AHTTLMNA | |
| SCHEMBL13292702 | 0.80 | MAPT (0.67) | MAPTALDH1A1KMT2AGAAHPGD | |
| SCHEMBL502583 | 0.80 | ALDH1A1 (0.78) | MAPTALDH1A1KMT2AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124229-A | Novel heterocyclic compounds for the treatment of inflammatory and allergic disorders | GLENMARK PHARMACEUTICALS SA (CH) | 2008-02-13 | — | — | CN | claimed |
| WO-2024259930-A9 | PHOSPHONATE COMPOUND AND MEDICAL USE THEREOF | 润佳（苏州）医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| WO-2024259930-A1 | PHOSPHONATE COMPOUND AND MEDICAL USE THEREOF | 润佳（苏州）医药科技有限公司 | 2024-12-26 | — | — | WO | disclosed |
| CN-118388480-A | 6-Arylquinazolin-4-amine and 6-arylpyridopyrimidine-4-amine derivatives and their use as PI3K delta covalent inhibitors | 西安交通大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-117285566-A | Phosphonate compound and medical application thereof | 润佳（苏州）医药科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| US-20220170904-A1 | SYSTEMS AND METHODS FOR MONITORING BIOLOGICAL TISSUE DEGRADATION | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |
| CN-107531701-A | Crystalline compounds as semicarbazide-sensitive amine oxidase (SSAO) enzyme inhibitors | 普罗克斯马根有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107530330-A | The treatment of pain | 普罗克斯马根有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107531702-A | Pharmaceutical salt forms of semicarbazide-sensitive amine oxidase (SSAO) inhibitors | 普罗克斯马根有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-104428305-A | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-101124229-B | Novel heterocyclic compounds for the treatment of inflammatory and allergic disorders | GLENMARK PHARMACEUTICALS SA | 2012-07-18 | — | — | CN | disclosed |
| CN-102232073-A | New compounds I | BIOVITRUM AB PUBL | 2011-11-02 | — | — | CN | disclosed |
| CN-101124229-A | Novel heterocyclic compounds for the treatment of inflammatory and allergic disorders | GLENMARK PHARMACEUTICALS SA (CH) | 2008-02-13 | — | — | CN | disclosed |
| US-5763404-A | LUTEINIZING HORMONE RELEASING HORMONE | UNIV TEXAS (US) | 1998-06-09 | — | — | US | disclosed |
| US-5470947-A | Lutenizing hormone-releasing hormone, contraceptives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0377665-B1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE | UNIV TEXAS (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0489581-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1992-06-10 | — | — | EP | disclosed |
| EP-0377665-A1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE. | UNIV TEXAS (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4935491-A | CONTRACEPTIVES WITH REDUCED SIDE EFFECTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-06-19 | — | — | US | disclosed |
| WO-1989001944-A1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1989-03-09 | — | — | WO | disclosed |