SCHEMBL8709148

SCHEMBL8709148

C=CC(OC(Br)CCCCCCCCC)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
HTR2A P28223 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
CSNK1E P49674 1/20 0.35
OPRM1 P35372 2/20 0.34
OPRD1 P41143 2/20 0.34
OPRK1 P41145 2/20 0.34
OPRL1 P41146 2/20 0.34
NAAA Q02083 2/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
KCNH2 Q12809 2/20 0.33
ASAH1 Q13510 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6811529 0.99 ALDH1A1 (0.35) ALDH1A1HTR2APRSS1PRSS2PRSS3
SCHEMBL8711760 0.88 AOC3 (0.35) ALDH1A1HTR2ASIGMAR1
SCHEMBL20534805 0.85 CSNK1E (0.39) ALDH1A1HTR2APRSS1PRSS2PRSS3
SCHEMBL20534622 0.84 CSNK1E (0.37) ALDH1A1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL8709294 0.83 CSNK1E (0.43) ALDH1A1HTR2APRSS1PRSS2PRSS3
SCHEMBL6811502 0.81 CSNK1E (0.41) ALDH1A1CSNK1EOPRM1OPRD1OPRK1
SCHEMBL8707831 0.81 ALDH1A1 (0.35) ALDH1A1HTR2APRSS1CSNK1EOPRM1
SCHEMBL6540703 0.78 ALDH1A1 (0.40) ALDH1A1HTR2A
SCHEMBL6541581 0.76 NPC1 (0.42) ALDH1A1HTR2ANPC1RAB9ASMN1; SMN2
SCHEMBL6541323 0.76 NPC1 (0.42) ALDH1A1HTR2ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5731395-A POLYMER CONTAINING DIVINYLBENZENE AND STYRENE COMPOUND ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed