SCHEMBL20534622

SCHEMBL20534622

C=CC(OC(CCCCC)OC(C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.37
ALDH1A1 P00352 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
HTR2A P28223 2/20 0.35
OPRM1 P35372 2/20 0.35
OPRD1 P41143 2/20 0.35
OPRK1 P41145 2/20 0.35
OPRL1 P41146 2/20 0.35
NAAA Q02083 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
HRH1 P35367 1/20 0.33
LMNA P02545 1/20 0.33
CNR2 P34972 1/20 0.33
CASR P41180 1/20 0.33
SLC37A4 O43826 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20534805 0.98 CSNK1E (0.39) CSNK1EALDH1A1SIGMAR1HTR2AOPRM1
SCHEMBL6811502 0.88 CSNK1E (0.41) CSNK1EALDH1A1OPRM1OPRD1OPRK1
SCHEMBL8709294 0.87 CSNK1E (0.43) CSNK1EALDH1A1HTR2AOPRM1OPRD1
SCHEMBL8707831 0.85 ALDH1A1 (0.35) CSNK1EALDH1A1SIGMAR1HTR2AOPRM1
SCHEMBL6811529 0.85 ALDH1A1 (0.35) CSNK1EALDH1A1SIGMAR1HTR2AOPRM1
SCHEMBL8709148 0.84 ALDH1A1 (0.37) CSNK1EALDH1A1SIGMAR1HTR2AOPRM1
SCHEMBL6540703 0.81 ALDH1A1 (0.40) ALDH1A1HTR2APOLBHRH1CASR
SCHEMBL27823090 0.78 LTA4H (0.41) HTR2ANPC1RAB9ASMN1; SMN2LMNA
SCHEMBL6541581 0.76 NPC1 (0.42) ALDH1A1HTR2ANPC1RAB9ASMN1; SMN2
SCHEMBL22654229 0.76 LMNA (0.35) ALDH1A1LMNACASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12385907-B2 Transition metal chelating beads ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2025-08-12 US claimed
EP-3948282-B1 TRANSITION METAL CHELATING BEADS ROCHE DIAGNOSTICS GMBH (DE) 2025-04-23 EP claimed
EP-3948282-A1 TRANSITION METAL CHELATING BEADS Roche Diagnostics GmbH (DE) 2022-02-09 EP claimed
US-20220009963-A1 TRANSITION METAL CHELATING BEADS ROCHE DIAGNOSTICS GMBH (DE) 2022-01-13 US claimed
CN-113646634-A Transition metal chelate beads 豪夫迈·罗氏有限公司 2021-11-12 CN claimed
WO-2020201089-A1 TRANSITION METAL CHELATING BEADS ROCHE DIAGNOSTICS GMBH (DE) 2020-10-08 WO claimed
EP-4707808-A2 SUPERPARAMAGNETIC AND HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS Roche Diagnostics GmbH (DE) 2026-03-11 EP disclosed
EP-3610262-B1 SUPERPARAMAGNETIC AND HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS ROCHE DIAGNOSTICS GMBH (DE) 2026-03-04 EP disclosed
US-12385907-B2 Transition metal chelating beads ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2025-08-12 US disclosed
EP-3948282-B1 TRANSITION METAL CHELATING BEADS ROCHE DIAGNOSTICS GMBH (DE) 2025-04-23 EP disclosed
CN-118649443-A Superparamagnetic and highly porous polymer particles for diagnostic applications 豪夫迈·罗氏有限公司 2024-09-17 CN disclosed
US-20230381743-A1 METHOD FOR PREPARING HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS ROCHE DIAGNOSTICS OPERATIONS, INC. 2023-11-30 US disclosed
US-11724246-B2 Method for preparing highly porous polymer particles for diagnostic applications ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2023-08-15 US disclosed
EP-3610263-A1 METHOD FOR PREPARING HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS Roche Diagnostics GmbH (DE) 2020-02-19 EP disclosed
US-20200038839-A1 METHOD FOR PREPARING HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2020-02-06 US disclosed
US-20200041502-A1 SUPERPARAMAGNETIC AND HIGHLY POUROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2020-02-06 US disclosed
CN-110741258-A Superparamagnetic and highly porous polymer particles for diagnostic applications 豪夫迈·罗氏有限公司 2020-01-31 CN disclosed
WO-2019141779-A1 HYPERCROSSLINKING WITH DIAMINE CROSSLINKERS F. HOFFMANN-LA ROCHE AG (CH) 2019-07-25 WO disclosed
WO-2018189287-A1 METHOD FOR PREPARING HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS ROCHE DIAGNOSTICS GMBH (DE) 2018-10-18 WO disclosed
WO-2018189286-A1 SUPERPARAMAGNETIC AND HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS ROCHE DIAGNOSTICS GMBH (DE) 2018-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12385907-B2 Transition metal chelating beads PHOSPHO1, PIGO, C9 CSNK1E 3358/4885ALDH1A1 2907/4885SIGMAR1 1617/4885
US-20220009963-A1 TRANSITION METAL CHELATING BEADS PHOSPHO1, PIGO, C9 CSNK1E 3358/4885ALDH1A1 2907/4885SIGMAR1 1617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.