SCHEMBL8709485

SCHEMBL8709485

CC1(C)OC(=O)C=C1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124562 0.72
SCHEMBL5316374 0.70
SCHEMBL14326907 0.70
SCHEMBL7637933 0.61
SCHEMBL218538 0.60 TSHR (0.36)
SCHEMBL11800450 0.59
SCHEMBL13143012 0.59 TSHR (0.35)
SCHEMBL28945704 0.58 LMNA (0.36)
SCHEMBL7235362 0.57 ALDH1A1 (0.33)
SCHEMBL9134737 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61100577-A None JP disclosed
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO INC (US) 2026-03-12 US disclosed
EP-0863890-A1 5-AMIDOMETHYL ALPHA, BETHA-SATURATED AND -UNSATURATED 3-ARYL BUTYROLACTONE ANTIBACTERIAL AGENTS PHARMACIA &amp; UPJOHN COMPANY (US) 1998-09-16 EP disclosed
US-5708169-A BACTERICIDES FOR TREATMENT OF GRAM POSITIVE INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 1998-01-13 US disclosed
WO-1997010235-A1 5-AMIDOMETHYL α, β-SATURATED AND -UNSATURATED 3-ARYL BUTYROLACTONE ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 1997-03-20 WO disclosed
JP-S61100577-A PRODUCTION OF AMINOFURANONE SAGAMI CHEM RES CENTER 1986-05-19 JP disclosed