Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 10/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713970 | 0.90 | ALDH1A1 (0.49) | HSD11B1L3MBTL1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL7866478 | 0.88 | MAPK1 (0.47) | SLC6A7HSD11B1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8441843 | 0.85 | ALDH1A1 (0.49) | HSD11B1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL13149365 | 0.82 | SLC6A7 (0.70) | SLC6A7KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL8711887 | 0.82 | ADRA2A (0.51) | SLC6A7HSD11B1KDM4EL3MBTL1HPGD | |
| SCHEMBL8711943 | 0.82 | CYP1A2 (0.55) | HSD11B1L3MBTL1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL7872821 | 0.77 | SMN1; SMN2 (0.43) | HSD11B1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL8658563 | 0.77 | HPGD (0.68) | HPGDALDH1A1TSHRKMT2A | |
| SCHEMBL7869762 | 0.75 | PRKAA2 (0.47) | SLC6A7HSD11B1KDM4EL3MBTL1HPGD | |
| SCHEMBL7873110 | 0.75 | PRMT5 (0.46) | HSD11B1KDM4EL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054140-A1 | NOVEL TEREPHTHALAMIDE DERIVATIVES | DONGWHA PHARMACEUTICAL IND. CO., LTD. (KR) | 1998-12-03 | — | — | WO | disclosed |