Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | PI4KA | P42356 | 7/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316382 | 0.76 | CDK1 (0.33) | ADORA2AADORA3CDK1CCNB1CCNE1 | |
| SCHEMBL25423776 | 0.71 | CDK1 (0.37) | ADORA2ACDK1CCNB1CCNE1CDK2 | |
| SCHEMBL21128128 | 0.71 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL24453637 | 0.70 | ADORA2A (0.42) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL763189 | 0.69 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL26348959 | 0.69 | AHCY (0.44) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL7938906 | 0.68 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL13347013 | 0.67 | CDK1 (0.41) | ADORA2AADORA3CDK1CCNB1CCNE1 | |
| SCHEMBL21504439 | 0.67 | PDE8B (0.52) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL21942687 | 0.66 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BADORA3PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007844-A2 | SCREENING ASSAY FOR THE IDENTIFICATION OF AGENTS WHICH ALTER EXPRESSION OF PTH-rP | OSTEOSCREEN (US) | 1998-02-26 | — | — | WO | disclosed |