Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45688 | 0.85 | — | — | |
| E968 SCHEMBL28649789 | 0.82 | LMNA (0.47) | LMNAL3MBTL1TDP1CA5ACA5B | |
| E968 SCHEMBL28654266 | 0.82 | LMNA (0.47) | LMNAL3MBTL1TDP1CA5ACA5B | |
| Ammonia Solution, Strong SCHEMBL10532387 | 0.82 | — | — | |
| SCHEMBL10535406 | 0.82 | — | — | |
| E968 SCHEMBL21173668 | 0.82 | LMNA (0.47) | LMNAL3MBTL1TDP1CA5ACA5B | |
| Mannitol SCHEMBL3887158 | 0.77 | LMNA (0.69) | LMNAL3MBTL1TDP1CA5ACA5B | |
| Adonitol SCHEMBL20481269 | 0.77 | LMNA (0.59) | LMNAL3MBTL1TDP1CA5ACA5B | |
| Mannitol SCHEMBL20572201 | 0.77 | LMNA (0.69) | LMNAL3MBTL1TDP1CA5ACA5B | |
| Sulfuric Acid SCHEMBL28863763 | 0.77 | LMNA (0.42) | LMNAL3MBTL1TDP1CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | disclosed |
| US-5733767-A | PURE HYDROLYTIC ENZYMES PREPARED BY CULTURING AEROBIC, GRAMNEGATIVE, ROD-SHAPED OBLIGATE ALKALIPHILIC BACTERIA HAVING SPECIFIED CHARACTERISTICS | GENENCOR INTERNATIONAL, INC. (US) | 1998-03-31 | — | — | US | disclosed |
| US-5719047-A | PREPARATION OF ALKALI-TOLERANT ENZYMES BY CULTURING SPECIFIED ALKALIPHILIC BACTERIA, SEPARATING BACTERIA FROM MEDIUM, RECOVERING ENZYMES | GIST-BROCADES, N.V. (NL) | 1998-02-17 | — | — | US | disclosed |
| EP-0473217-B1 | Gram-negative alkaliphilic microorganisms | GENENCOR INT (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5571716-A | AEROBIC BACTERIA, PRODUCING ALKALI-TOLERANT ENZYMES | GIST-BROCADES, N.V. (NL) | 1996-11-05 | — | — | US | disclosed |
| US-5514575-A | ALKALI TOLERANT ENZYMES PRODUCED BY BACTERIA | GIST-BROCADES, N.V. (NL) | 1996-05-07 | — | — | US | disclosed |
| US-5459062-A | Alkali tolerant bacteria isolated from soda lake environment, used to produce alkali tolerant enzymes | GIST-BROCADES, N.V. (NL) | 1995-10-17 | — | — | US | disclosed |
| EP-0473217-A1 | Gram-negative alkaliphilic microorganisms | GIST-BROCADES N.V. (NL) | 1992-03-04 | — | — | EP | disclosed |
| WO-1992002613-A1 | GRAM-NEGATIVE ALKALIPHILIC MICROORGANISMS | GIST-BROCADES N.V. (NL) | 1992-02-20 | — | — | WO | disclosed |